No effects of GAA on osmotic fragility of erythrocytes

No effects of GAA on osmotic fragility of erythrocytes

Serum levels of guanidinoacetic acid (GAA) were measured in 22 patients on maintenance hemodialysis prior to dialysis. The mean level was 0.699 ± 0.25 mg/dl, which represents a 3-fold increase above normal. Addition of GAA to blood from normal volunteers and incubation for 3 and 48 h at 37°C did not influence osmotic fragility of erythrocytes in vitro.

Gold CH, Viljoen M, Mzamane DV. The lack of effect of guanidinoacetic acid on in vitro osmotic fragility of erythrocytes. Nephron. 1982;31(1):17-19. doi:10.1159/000182600

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