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Reducing myopathies via GAA

Performance and processing advantages have been noted in meat animal production when excess arginine is available in the diet. In addition, dietary inclusion of guanidinoacetic acid (GAA) has provided insight on sparing arginine for broiler chickens. Therefore, a study was conducted to assess dietary inclusion of GAA on broiler breast myopathy prevalence. Dietary treatments were […]

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GAA affects water holding capacity

The current study was carried out to detect the effect of dietary guanidinoacetic acid (GAA) supplementation on carcass characteristics and meat quality in finishing pigs fed different dietary crude protein (CP) levels. Sixty-four barrows with an initial body weight of 73.05 ± 2.34 kg were randomly allocated into 1 of 4 dietary treatments in a […]

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GAA for intestinal function

The current study is designed to investigate dietary guanidinoacetic acid (GAA) supplementation on the growth performance, intestinal histomorphology, and jejunum mucosal barrier function of broilers that subjected to chronic heat stress (HS). A total of 192 male broilers (28-d-old) were randomly allocated to four groups. A chronic HS model (at a temperature of 32 °C […]

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GAA supplementation and lactation

Considering the high energy demand of lactation and the potential of guanidinoacetic acid (GAA) addition on the increase in creatine supply for cows, the study investigated the effects of 0, 0.3, 0.6 and 0.9 g kg−1 DM of GAA supplementation on lactation performance, nutrient digestion and ruminal fermentation in dairy cows. The study used fourty mid-lactation multiparous […]

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GAA, nitrogen retention and methionine flux

Six ruminally cannulated Holstein steers (256 ± 14 kg) were used in a 6 × 6 Latin square design to assess effects of guanidinoacetic acid (GAA) supplementation on N retention and methionine (Met) methyl group flux in growing cattle fed corn-based diets. Factorial treatments were 2 levels of Met (0 or 5 g/d) and 3 […]

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GAA-driven daily gain and feed efficiency

In this study, the authors investigated the effects of guanidinoacetic acid (GAA) and betaine (BT) on growth performance, nutrient digestion, energy-nitrogen metabolism, and microbial protein synthesis in lambs. Forty-eight 3-month-old Dorper × Thin-tailed Han first crossbred generation ram lambs with similar body weight (22.03 ± 1.3 kg; mean ± SD) were randomly divided into 4 groups. […]

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GAA, betaine and creatine for cardioprotection

This study aimed to determine how guanidinoacetic acid (GAA) or its combined administration with betaine or creatine influences the cardiac function, morphometric parameters, and redox status of rats subjected to high-intensity interval training (HIIT). This research was conducted on male Wistar albino rats exposed to HIIT for 4 weeks. The animals were randomly divided into […]

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GAA improves growth performance

Guanidinoacetic acid (GAA) exists naturally as a precursor of creatine, which possesses several biological functions. In the present study, the effects of dietary GAA supplementation on skeletal muscle mass and meat quality of lambs were investigated. The GAA supplementation increased final body weight, promoted muscle mass and changed the distribution of myofiber size. Meanwhile, elevated […]

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GAA intake affects free amino acid profile

As a nutritive feed additive, guanidine acetic acid (GAA) participates in the metabolism of energy and proteins. This study aimed to investigate the effects of GAA on growth performance, organ index, plasma and tissue free amino acid profiles, and related metabolites in finishing pigs. A total of 72 crossbred pigs (body weight 86.59 ± 1.16 kg) were randomly assigned […]

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Dietary GAA and growth in lambs

Guanidinoacetic acid (GAA) is the only precursor for the creatine synthesis of vertebrates. Creatine (Cr) and phosphocreatine (PCr) are able to provide energy for the rapid growth and development of the muscle tissue. This study evaluated the effects of dietary different levels GAA on growth performance, GAA absorption and creatine metabolism of lambs. Twenty-four 3-month-old […]

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