GAA Research Library

Growth, muscle creatine and supplemental GAA

A simple and reliable method of extracting creatine from muscle for analysis as creatinine is described. In the absence of exogenous glycocyamine, growth was accelerated but muscle creatine levels were reduced in rats fed folacin and B12, either alone, or with methionine; growth was also accelerated in rats given folacin and B12 with choline, however, […]

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The synthesis of arginine from GAA

Guanidoacetic acid is an important precursor of creatine in the organism. Other than this, little is known regarding the metabolism of this compound. Guanidoacetic acid is formed in the body by the transfer of the amidine group of arginine to glycine according to the following reaction, arginine + glycine = guanidoacetic acid + ornithine, which […]

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GAA-betaine affects high-energy phosphate in muscle

A single dose of glycocyamine and betaine increased the creatine phosphate levels in the skeletal muscles of adult rats to a slight but statistically significant extent. The creatine phosphate returned to control values between 6 and 12 days. Daily ingestion of glycocyamine over a 98-day period produced the same, but no greater increase, in creatine […]

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