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Fasting reduces GAA levels

The authors studied the effects of 24-h fasting on serum levels of GAA, creatine, and creatinine in 24 non-vegetarian healthy adults. Blood was taken before and following an intervention, with levels corrected for fasting-induced changes in plasma volume. Food abstention induced a significant decrease in serum GAA by 39.5% (p < 0.001), while creatinine levels increased by […]

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Arginine, GAA and citrulline for bone morphology

The alterations in feed ingredients and the nutrient matrix to produce reduced-protein diets may affect bone morphology and mineralization in laying hens. This study was implemented to determine the effects of L-arginine (Arg), guanidinoacetic acid (GAA), and L-citrulline (Cit) supplementation to Arg-deficient reduced-protein diets on bone morphology, strength, and mineralization status of laying hens. Individually […]

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GAA, fermentation and nutrient flow

Eight dual-flow continuous culture fermenters were used in 2 periods (7 adaptation and 3 sampling days) to evaluate the effect of guanidinoacetic acid (GAA) on rumen microbial fermentation and nutrient degradability in dairy and beef cattle. The study was conducted as a completely randomized block design. Treatments (n = 4) were arranged in a 2 […]

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GAA and gas composition

This study explores whether guanidinoacetic acid (GAA) addition can regulate nutrient degradability, rumen fermentation characteristics, and gas composition in two sheep-fattening diets. A 2 × 8 factorial in vitro culture was examined to determine the effects of GAA addition at the following levels of 0%, 0.03%, 0.05%, 0.07%, 0.09%, 0.11%, 0.13%, and 0.15% of two […]

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GAA and creatine in hybrid striped bass

The effects of dietary supplementation of creatine and guanidinoacetic acid (GDA) have been studied to a limited extent in various fish species including red drum (Sciaenops ocellatus) and hybrid striped bass (HBS) (Morone saxatilis x M. chrysops). However, in HSB, there is a need to better understand the impact of creatine and GDA supplementation at […]

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GAA and rumen fermentation profile

The objective of this study was to evaluate the effect of different percentages of alfalfa (Medicago sativa L.) hay (AH) and doses of guanidinoacetic acid (GAA) in the diet on the mitigation of greenhouse gas production, the in vitro rumen fermentation profile and methane (CH4) conversion efficiency. AH percentages were defined for the diets of […]

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GAA affects tissue bound amino acid profiles

This study aims to investigate the effects of guanidine acetic acid (GAA) on carcass traits, plasma biochemical parameters, tissue antioxidant capacity, and tissue-bound amino acid contents in finishing pigs. Seventy-two 140-day-old (body weight 86.59 ± 1.16 kg) crossbred pigs (Duroc × Landrace × Large White) were randomly assigned into four treatments with six replicate pens […]

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Arginine, GAA and ascites susceptibility

In order to evaluate the effects of ARG sources (arginine [ARG] and Guanidinoacetic acid [GAA]) and phenylalanine (PHE) supplementation on performance, susceptibility to ascites, intestinal morphology, and nutrient digestibility in the cold-stressed broilers fed a canola meal (CM)-based diet, a 2×2 factorial experiment with four treatments was conducted. The dietary treatments included CM-based diet + […]

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Beneficial performance in heat stress by GAA

Dietary guanidinoacetic acid (GAA) has been shown to affect creatine (Cr) metabolic pathways resulting in increased cellular Cr and hitherto broiler performances. Yet, the impact of dietary GAA on improving markers of oxidative status remains equivocal. A model of chronic cyclic heat stress, known to inflict oxidative stress, was employed to test the hypothesis that […]

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GAA and lactation performance

Considering the high energy demand of lactation and the potential of guanidinoacetic acid (GAA) addition on the increase in creatine supply for cows, the present study investigated the effects of 0, 0.3, 0.6 and 0.9 g kg-1 dry matter (DM) of GAA supplementation on lactation performance, nutrient digestion and ruminal fermentation in dairy cows. The […]

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