GAA, nitrogen retention and methionine flux
Six ruminally cannulated Holstein steers (256 ± 14 kg) were used in a 6 × 6 Latin square design…
GAA-driven daily gain and feed efficiency
In this study, the authors investigated the effects of guanidinoacetic acid (GAA) and betaine (BT) on growth performance, nutrient…
GAA and creatine in aquafeeds
Creatine is an amino acid derivate commonly found in vertebrate muscle tissue. Creatine facilitates the recycling of adenosine triphosphate…
GAA, betaine and creatine for cardioprotection
This study aimed to determine how guanidinoacetic acid (GAA) or its combined administration with betaine or creatine influences the…
About GAA Science
Physiological roles of GAA
GAA could affect many aspects of human metabolism, including cellular bioenergetics, neuromodulation, or oxidant-antioxidant status.
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GAA Fundamentals
Guanidinoacetic acid (also known as glycocyamine or betacyamine) is a normal constituent of human blood, urine, and breast milk.
Being a natural amino acid derivative and a metabolite in the urea cycle, GAA also appears as an intermediate in metabolic pathways of several amino acids, including glycine, serine and arginine. GAA is direct precursor of creatine, a key substrate for cellular energy.
- CAS Registry # 362-97-6
- PubChem CID 763
- Chemical formula C3H7N3O2
- Molar mass 117.1 g/mol
The natural daily turnover of GAA is balanced between endogenous production and kidney excretion; only a minimal amount of GAA is available from food sources (e.g. 10 mg of GAA per kg of meat).
Dr. Sergej Ostojic
GAA-science.com was created and administered by a research group headed by Sergej M. Ostojic, MD, PhD, Professor of Nutrition at the University of Agder and the University of Novi Sad, who has been involved in GAA research for over a decade.
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