Physiological roles of GAA and its relationship with arginine
The role of guanidinoacetic acid (GAA) and its relationship with arginine was reviewed in order to define a replacement…
GAA supplementation and nitrogen retention
Creatine stores high-energy phosphate bonds in muscle and is synthesized in the liver through methylation of guanidinoacetic acid (GAA).…
Urinary GAA significantly altered in ASD
Autism spectrum disorder (ASD) is a group of early-onset neurodevelopmental disorders. So far, there is no valid biomarker for…
GAA and betaine for growth performance
This study evaluated the influences of guanidinoacetic acid (GAA) and betaine (BT) on growth performance, nutrient digestion and ruminal…
About GAA Science
Physiological roles of GAA
GAA could affect many aspects of human metabolism, including cellular bioenergetics, neuromodulation, or oxidant-antioxidant status.
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GAA Fundamentals
Guanidinoacetic acid (also known as glycocyamine or betacyamine) is a normal constituent of human blood, urine, and breast milk.
Being a natural amino acid derivative and a metabolite in the urea cycle, GAA also appears as an intermediate in metabolic pathways of several amino acids, including glycine, serine and arginine. GAA is direct precursor of creatine, a key substrate for cellular energy.
- CAS Registry # 362-97-6
- PubChem CID 763
- Chemical formula C3H7N3O2
- Molar mass 117.1 g/mol
The natural daily turnover of GAA is balanced between endogenous production and kidney excretion; only a minimal amount of GAA is available from food sources (e.g. 10 mg of GAA per kg of meat).
Dr. Sergej Ostojic
GAA-science.com was created and administered by a research group headed by Sergej M. Ostojic, MD, PhD, Professor of Medicine at the University of Novi Sad and the University of Belgrade, who has been involved in GAA research for many years.
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